Penn State Nittany Lions

Notre Dame among heavy favorites in Week 2 college football odds

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The upside of the Notre Dame Fighting Irish losing a thriller in their opener against Texas is that they are returning home this week, where they have been covering spreads consistently. Notre Dame is listed as a 28-point favorite against the Nevada Wolf Pack with a total of 60.5 points at sportsbooks monitored by OddsShark.com.

Notre Dame is 6-0 straight-up and 5-1 against the spread in its last six games at home, according to the OddsShark College Football Database. The Irish are 8-2 SU and 6-3-1 ATS in their last 10 September home games. The total went over in nine of those 10 games. Notre Dame is just 3-6-1 ATS in their last 10 outings as a favorite of at least 21 points. Nevada is 9-3 ATS in its last 12 games on the road.

The Tennessee Volunteers are 11-point favorites, with a 54.5 total, against the Virginia Tech Hokies at Bristol Motor Speedway. According to website PredictionMachine.com the Volunteers win this matchup SU 89.2% of the time at an average score of 35.8-20.8. The total has gone under for bettors in five of Tennessee’s last seven games after a win.

The No. 1 Alabama Crimson Tide are 29-point home favorites against the Western Kentucky Hilltoppers, with a 61.5-point total. Alabama is 13-0 SU over its last 13 games but only 2-5 ATS during its last seven home games. Western Kentucky is 5-0 ATS in its last five games after a win. The total has gone over in WKU’s last four road games.

The SEC has two conference matchups in Week 2. The Mississippi State Bulldogs are 6.5-point favorites against the South Carolina Gamecocks, with a total of 45. The Gamecocks are 7-0 SU and 6-1 ATS in their last seven games vs. MSU. Mississippi State is 5-0 SU in its last five games after a loss. The total has gone under in four of South Carolina’s last five games.

The Florida Gators are 16-point favorites against the Kentucky Wildcats with a total of 47.5. Florida is 7-2 SU and ATS in its last nine conference games, and is 13-6-1 ATS vs. Kentucky since 1995. The total has gone under in six of Florida’s last eight games.

The Pittsburgh Panthers are six-point favorites against the Penn State Nittany Lions, with a 48.5-point total. Pittsburgh is 8-1 SU in its last nine games in Week 2. Penn State is also in an 0-9 ATS slump over their last nine road games. The total has gone under in three of Pittsburgh’s last four games against the Big Ten.

The Louisville Cardinals are 14.5-point road favorites against the Syracuse Orange, with a 69.0 total. Louisville is 16-4 SU and 13-7 ATS in their last 20 September games, but that sample includes a 1-4 ATS trend in Week 2 games. Syracuse is 5-0 ATS in their last five home games. The total has gone over in five of Louisville’s last six games.

Which Michigan, Penn State teams will show up?

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In a matchup of perennial powers, Michigan and Penn State link up from State College and Pro Football Focus dives deep into the numbers to show how unpredictable these two teams can be.